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WHAT
IS HABBATUS SAUDA' / HABBAH BARAKAH / NIGELLA SATIVA / BLACK SEED?
Ali BH, Blunden G.: Department of
Veterinary Medicine, King Saud University, Buraydah, Al Gaseem 81999,
Saudi Arabia reports that:-
The seeds of nigella sativa / black
seed, commonly known as black seed or black cumin, are used in
folk (herbal) medicine all over the world for the treatment and
prevention of a number of diseases and conditions that include asthma, diarrhoea and dyslipidaemia. This article reviews the
main
reports of the pharmacological and toxicological properties of Nigella
sativa and its constituents.
The
nigella sativa
/ black seeds contain
both fixed and essential oils, proteins, alkaloids and saponin. Much of
the biological activity of the seeds has been shown to be due to
thymoquinone, the major component of the essential oil, but which is
also present in the fi ed oil. The pharmacological actions of the crude
extracts of the seeds and some of its active constituents, e.g.
volatile oil and thymoquinone) that have been reported include protection
against nephrotoxicity and hepatotoxicity induced by either disease or
chemicals. The seeds/oil have antiinflammatory, analgesic, antipyretic,
antimicrobial and antineoplastic activity. The nigella sativa oil
decreases blood pressure and increases respiration.
Treatment
of rats with the seed extract for up to 12 weeks has been reported to
induce changes in the haemogram that include an increase in both the
packed cell volume (PCV) and haemoglobin (Hb), and a decrease in plasma concentrations of
cholesterol, triglycerides and glucose. The seeds are characterized by
a
very low degree of toxicity. Two cases of contact
dermatitis in two individuals have been reported following topical use.
Administration
of either the seed extract or its oil has been shown not to induce
significant adverse effects on liver or kidney functions. It would
appear that the beneficial
effects
of the use of the seeds and thymoquinone might be related to their
cytoprotective and antioxidant actions, and to their effect on some
mediators of inflammation.
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PRODUK TERBAIK HERBA HABBATUS SAUDA' DARI TIMUR TENGAH
Kapsul Habbatussauda
Madu Habbatussauda
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